The main aim of our clinical research is to ameliorate the management of neuromuscular patients trough identifying either new diagnostic markers as new therapies direct not only against disease causes but also to reduce symptoms or to improve patient autonomy often reduced by disability . All these through : -Consulting for outpatients with neuromuscular diseases ( muscle, peripheral nerve diseases and ALS ) Intravenous drug therapy for out patients ( file F) Diagnosis and therapeutic strategies on inpatients affected by neuromuscular diseases . Multi-centric clinical studies to evaluate new therapies for neuromuscular diseases Observational multi-centric studies on diagnostic flow chard on peripheral neuropathies Clinical studies for evaluating management strategies of disability treatment in neuromuscular diseases (rehabilitation therapy, PEG ).